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Impact of Polyelectrolyte Structure on the Shape of Nanoassemblies with Cationic Peptides

Ferstl, Matthias ; Drechsler, Markus ; Rachel, Reinhard ; Rischer, M. ; Engel, J. ; Backofen, Michael ; Goepferich, Achim



Abstract

We investigated how the structure of nanofibers, resulting from interactions between anionic polyelectrolytes and cationic peptides, relies on the properties of the polyelectrolyte component. By using hyaluronate (H), carboxymethylcellulose (CMC), xanthan (X), and ozarelix (O), a cationic decapeptide, we determined the influence of characteristic polyelectrolyte parameters such as size and charge ...

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