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Novel in vitro model for combined effects of alcohol and free fatty acids on hepatocellular lipid accumulation and inflammation

Mahli, Abdo (2015) Novel in vitro model for combined effects of alcohol and free fatty acids on hepatocellular lipid accumulation and inflammation. PhD, Universität Regensburg.

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Date of publication of this fulltext: 27 Feb 2015 17:08

Abstract (English)

Alcoholic steatohepatitis (ASH) and nonalcoholic steatohepatitis (NASH) are the most frequent conditions leading to elevated liver enzymes and liver cirrhosis, respectively, in the Western world. However, despite strong epidemiological evidence for combined effects of alcohol consumption and hepatic lipid accumulation on the progression of liver injury, the mutual interaction of the ...

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Translation of the abstract (German)

Die Alkoholische Steatohepatitis (ASH) und Nicht-Alkoholische Steatohepatitis (NASH) sind in der westlichen Welt die häufigsten Erkrankungen, die zu erhöhten Leberenzymen und zur Leberzirrhose führen. Doch trotz starker epidemiologischer Evidenz für kombinierte Effekte von Alkoholkonsum und hepatischerLipidakkumulation auf die Progression der Leberschädigung, ist die gegenseitige Wechselwirkung ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:27 February 2015
Referee:Prof. Dr. Sigurd Elz and Prof. Dr. Claus Hellerbrand
Date of exam:18 December 2013
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Chemistry and Pharmacy > Institute of Pharmacy
Keywords:Alkohol, Ethanol, Lipide, Steatosis, Steatohepatitis, CYP2E1, Autophagie
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:29459
Owner only: item control page

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