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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-299626
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.29962
Zusammenfassung
The complement system is an essential part of the innate immune system by acting as a first line of defense which is stabilized by properdin, the sole known positive regulator of the alternative complement pathway. Dysregulation of complement can promote a diversity of human inflammatory diseases which are treated by complement inhibitors. Here, we generated a novel blocking monoclonal antibody ...
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