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Systematic structural and functional characterization of the family of Geranylgeranylglyceryl Phosphate Synthase-like enzymes

URN to cite this document:
urn:nbn:de:bvb:355-epub-299904
Peterhoff, David
Date of publication of this fulltext: 21 May 2014 12:57


Abstract (English)

A characteristic difference between the three phylogenetic domains of life is the chemical composition of the lipids forming their cell membranes. In Bacteria and Eukarya phospholipids are based on a sn-glycerol-3-phosphate (G3P) which is esterified with two fatty acids, while in phospholipids from Archaea the enantiomer sn-glycerol-1-phosphate (G1P) forms two ether-bonds with isoprenoid chains. ...

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Translation of the abstract (German)

Ein charakteristisches Unterscheidungsmerkmal zwischen den drei Domänen des Lebens ist die Zusammensetzung ihrer Zellmembranen. Die Phospholipide von Bakterien und Eukaryoten basieren auf sn-Glycerin-3-Phosphat (G3P), welches mit zwei Fettsäuren verestert ist, während in den Phospholipiden von Archaeen das Enantiomer sn-Glycerin-1-Phosphat (G1P) zwei Etherbindungen mit Isoprenolen ausbildet. ...

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