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Analysis of human urine reveals metabolic changes related to the development of acute kidney injury following cardiac surgery

Zacharias, Helena, Schley, Gunnar, Hochrein, Jochen, Klein, Matthias S., Köberle, Carmen, Eckardt, Kai-Uwe, Willam, Carsten, Oefner, Peter J. and Gronwald, Wolfram (2013) Analysis of human urine reveals metabolic changes related to the development of acute kidney injury following cardiac surgery. Metabolomics 9 (3), pp. 697-707.

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Abstract

Acute kidney injury (AKI) is a frequent complication of sepsis, major surgery or nephrotoxic medication use. It is associated with high morbidity and mortality. In an effort to identify novel biomarkers capable of predicting the development of AKI after cardiac surgery with cardiopulmonary bypass use, urine specimens were collected before and at 4 and 24 h after surgery from 106 patients and ...

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Item type:Article
Date:1 June 2013
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Identification Number:
ValueType
10.1007/s11306-012-0479-4DOI
Keywords:Acute kidney injury (AKI); Metabolomics; NMR spectroscopy; Classification
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:30524
Owner only: item control page
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