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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-305292
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.30529
Zusammenfassung
Aberrant regulation of the Wnt/β-catenin pathway has an important role during the onset and progression of colorectal cancer, with over 90% of cases of sporadic colon cancer featuring mutations in APC or β-catenin. However, it has remained a point of controversy whether these mutations are sufficient to activate the pathway or require additional upstream signals. Here we show that colorectal ...
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