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NMR metabolomic analysis of dairy cows reveals milk glycerophosphocholine to phosphocholine ratio as prognostic biomarker for risk of ketosis

Klein, Matthias S. ; Buttchereit, Nina ; Miemczyk, Sebastian P ; Immervoll, Ann-Kathrin ; Louis, Caridad ; Wiedemann, Steffi ; Junge, Wolfgang ; Thaller, Georg ; Oefner, Peter J. ; Gronwald, Wolfram



Abstract

Ketosis is a common metabolic disease in dairy cows. Diagnostic markers for ketosis such as acetone and beta-hydroxybutyric acid (BHBA) are known, but disease prediction remains an unsolved challenge. Milk is a steadily available biofluid and routinely collected on a daily basis. This high availability makes milk superior to blood or urine samples for diagnostic purposes. In this contribution, we ...

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