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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-323605
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.32360
Zusammenfassung
MicroRNAs (miRNAs) guide Argonaute (Ago) proteins to distinct target mRNAs leading to translational repression and mRNA decay. Ago proteins interact with a member of the GW protein family, referred to as TNRC6A-C in mammals, which coordinate downstream gene-silencing processes. The cytoplasmic functions of TNRC6 and Ago proteins are reasonably well established. Both protein families are found in ...
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