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Disease burden and risk profile in referred patients with moderate chronic kidney disease: composition of the German Chronic Kidney Disease (GCKD) cohort

Titze, S. ; Schmid, M. ; Köttgen, Anna ; Busch, M. ; Floege, J. ; Wanner, C. ; Kronenberg, F. ; Eckardt, K. U. ; Eckardt, K. U. ; Titze, S. ; Prokosch, H. U. ; Barthlein, B. ; Beck, A. ; Ganslandt, T. ; Gefeller, O. ; Schmid, M. ; Koster, J. ; Malzer, M. ; Schlieper, G. ; Eitner, F. ; Meisen, S. ; Kehl, K. ; Arweiler, E. ; Floege, J. ; Schaeffner, E. ; Baid-Agrawal, S. ; Schindler, R. ; Titze, S. ; Hubner, S. ; Dienemann, T. ; Hilgers, K. F. ; Eckardt, K. U. ; Köttgen, Anna ; Schultheiss, U. ; Walz, G. ; Kielstein, J. T. ; Lorenzen, J. ; Haller, H. ; Sommerer, C. ; Zeier, M. ; Busch, M. ; Paul, K. ; Wolf, G. ; Hilge, R. ; Sitter, T. ; Krane, V. ; Schmiedeke, D. ; Toncar, S. ; Wanner, C. ; Ekici, A. B. ; Reis, A. ; Forer, L. ; Schönherr, S. ; Weissensteiner, H. ; Kollertits, Barbara ; Raschenberger, J. ; Kronenberg, F. ; Gronwald, Wolfram ; Zacharias, Helena ; Oefner, Peter J.



Abstract

Background A main challenge for targeting chronic kidney disease (CKD) is the heterogeneity of its causes, co-morbidities and outcomes. Patients under nephrological care represent an important reference population, but knowledge about their characteristics is limited. Methods We enrolled 5217 carefully phenotyped patients with moderate CKD [estimated glomerular filtration rate (eGFR) 30–60 ...

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