Zusammenfassung
In an effort to develop a non-radioactive alternative to the [H-3]tiotidine and [I-125] iodoaminopotentidine binding assays for the histamine H-2-receptor (H2R), primary amines related to aminopotentidine were prepared and coupled with the succinimidyl esters of the bulky fluorescent dyes S0536 and BODIPY (R) 650/665-X. The primary amines exhibited different degrees of antagonistic potency at the ...
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