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Programmable biodegradable implants

Vogelhuber, W., Rutunno, P., Magni, E., Gazzaniga, A., Spruss, Thilo, Bernhardt, Günther, Buschauer, Armin and Goepferich, Achim (2001) Programmable biodegradable implants. Journal of Controlled Release 73 (1), pp. 75-88.

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Other URL: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T3D-42Y12G0-8&_user=616165&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000032338&_version=1&_urlVersion=0&_userid=616165&md5=0d67c4e6c030cf78f993ee22bec70c83


Pulsatile release implants were developed that release substances up to 58 days post implantation. With a cylindrical size of 2 mm diameter and 1.8 mm height the matrices can carry as much as 1 mg of drug and allow even for intracranial implantation into a rodent model. The matrices are made of materials that have been used for parenteral applications in humans before such as surface eroding ...


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Item type:Article
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
Keywords:Brain cancer; Vaccination; Programmable release; Biodegradable polymer; Pulsatile release
Dewey Decimal Classification:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:3404
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