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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-340425
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.34042
Zusammenfassung
Eukaryotic RNA polymerase I (Pol I) is specialized in rRNA gene transcription synthesizing up to 60% of cellular RNA. High level rRNA production relies on efficient binding of initiation factors to the rRNA gene promoter and recruitment of Pol I complexes containing initiation factor Rrn3. Here, we determine the cryo-EM structure of the Pol I-Rrn3 complex at 7.5 angstrom resolution, and compare ...
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