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Inducing anti-tumor cytokines and an immune response in melanoma by inhibition of MIA using the peptide AR71

Riechers, A., Schmidt, J., Dettmer, Katja, Oefner, Peter J., Jachimczak, P., Schneider, A. and Bosserhoff, Anja-Katrin (2013) Inducing anti-tumor cytokines and an immune response in melanoma by inhibition of MIA using the peptide AR71. Eur J Dermatol 23 (6), pp. 820-825.

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Other URL: http://www.jle.com/fr/revues/ejd/e-docs/inducing_anti_tumor_cytokines_and_an_immune_response_in_melanoma_by_inhibition_of_mia_using_the_peptide_ar71_299346/article.phtml


Abstract

Malignant melanoma is known for its aggressive metastatic spread and suppression of the host immune system. Immunosuppression in melanoma is mediated in part by the protein melanoma inhibitory activity (MIA). Objectives: In this study, we assessed the in vitro and in vivo efficacy of the MIA-inhibitory peptide AR71 in the inhibition of MIA-induced immunosuppression. This follows a previous study ...

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Item type:Article
Date:November 2013
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
10.1684/ejd.2013.2234DOI
24413571PubMed ID
Keywords:MIA; cytokine; immunosuppression; malignant melanoma; peptide inhibitor
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:34104
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