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The role of inflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways

Schmelzer, K. R., Wheelock, A. M., Dettmer, Katja, Morin, D. and Hammock, B. D. (2006) The role of inflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways. Environmental Health Perspectives 114 (9), pp. 1354-1360.

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Date of publication of this fulltext: 12 Aug 2016 11:50

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Other URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570074/


Abstract

Ambient air is polluted with a mixture of pulmonary toxicants. Previous studies indicate that prior exposure to atmospheric oxidant pollutants such as ozone may significantly alter the response to other pollutants, such as 1-nitronaphthalene (1-NN). 1-NN, a component of the particulate exhaust from diesel engines, has been found at low concentrations in ambient air. Using a metabolomic approach, ...

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Item type:Article
Date:September 2006
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Identification Number:
ValueType
16966088PubMed ID
10.1289/ehp.8373DOI
Keywords:1-nitronaphthalene, arachidonic acid, cyclooxygenase, inflammatory mediators, linoleic acid, lipoxygenase, ozone
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:34325
Owner only: item control page

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