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Nested effects models for high-dimensional phenotyping screens

Markowetz, F., Kostka, D., Troyanskaya, O. G. and Spang, Rainer (2007) Nested effects models for high-dimensional phenotyping screens. Bioinformatics 23 (13), i305-i312.

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Date of publication of this fulltext: 12 Aug 2016 12:07

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Other URL: http://bioinformatics.oxfordjournals.org/content/23/13/i305.long


Abstract

Motivation: In high-dimensional phenotyping screens, a large number of cellular features is observed after perturbing genes by knockouts or RNA interference. Comprehensive analysis of perturbation effects is one of the most powerful techniques for attributing functions to genes, but not much work has been done so far to adapt statistical and computational methodology to the specific needs of ...

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Item type:Article
Date:1 July 2007
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Identification Number:
ValueType
17646311PubMed ID
10.1093/bioinformatics/btm178DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:34328
Owner only: item control page

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