Go to content
UR Home

The role of selection in the evolution of human mitochondrial genomes

Kivisild, T. ; Shen, P. ; Wall, D. P. ; Do, B. ; Sung, R. ; Davis, K. ; Passarino, G. ; Underhill, P. A. ; Scharfe, C. ; Torroni, A. ; Scozzari, R. ; Modiano, D. ; Coppa, A. ; de Knijff, P. ; Feldman, M. ; Cavalli-Sforza, L. L. ; Oefner, Peter J.


High mutation rate in mammalian mitochondrial DNA generates a highly divergent pool of alleles even within species that have dispersed and expanded in size recently. Phylogenetic analysis of 277 human mitochondrial genomes revealed a significant (P < 0.01) excess of rRNA and nonsynonymous base substitutions among hotspots of recurrent mutation. Most hotspots involved transitions from guanine to ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons