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Transition event statistics in genetics and disordered kinetics. Theoretical approaches for extracting rate distributions from experimental data

Vlad, M. O., Oefner, Peter J. and Ross, J. (2006) Transition event statistics in genetics and disordered kinetics. Theoretical approaches for extracting rate distributions from experimental data. Journal of Physical Chemistry B 110 (38), pp. 18945-18952.

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Other URL: http://pubs.acs.org/doi/pdf/10.1021/jp0600458


Abstract

We study the analogies between the theory of rate processes in disordered systems and the overdispersed molecular clocks in evolutionary biology. A biological “molecular clock” expresses the statistics of the number of amino acid or nucleotide substitutions during evolution. Random variations of the evolution rates lead to statistical (overdispersed) molecular clocks which are described by random ...

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Item type:Article
Date:5 September 2006
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Identification Number:
ValueType
16986888PubMed ID
10.1021/jp0600458DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:34343
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