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Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis

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Cohen, C. D. ; Lindenmeyer, M. T. ; Eichinger, F. ; Hahn, A. ; Seifert, M. ; Moll, Anton G. ; Schmid, H. ; Kiss, E. ; Grone, E. ; Grone, H. J. ; Kretzler, M. ; Werner, T. ; Nelson, P. J.
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Date of publication of this fulltext: 18 Aug 2016 06:01


BACKGROUND: Diabetic nephropathy (DN) is a complex and chronic metabolic disease that evolves into a progressive fibrosing renal disorder. Effective transcriptomic profiling of slowly evolving disease processes such as DN can be problematic. The changes that occur are often subtle and can escape detection by conventional oligonucleotide DNA array analyses. METHODOLOGY/PRINCIPAL FINDINGS: We ...


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