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Selecting normalization genes for small diagnostic microarrays

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Jaeger, J. ; Spang, Rainer
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Date of publication of this fulltext: 19 Aug 2016 13:33


Background Normalization of gene expression microarrays carrying thousands of genes is based on assumptions that do not hold for diagnostic microarrays carrying only few genes. Thus, applying standard microarray normalization strategies to diagnostic microarrays causes new normalization problems. Results In this paper we point out the differences of normalizing large microarrays and small ...


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