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Synergy of interleukin 10 and toll-like receptor 9 signalling in B cell proliferation: Implications for lymphoma pathogenesis

Feist, M., Kemper, J., Taruttis, Franziska, Rehberg, Thorsten, Engelmann, Julia C. , Gronwald, Wolfram, Hummel, Michael, Spang, Rainer and Kube, Dieter (2017) Synergy of interleukin 10 and toll-like receptor 9 signalling in B cell proliferation: Implications for lymphoma pathogenesis. International Journal of Cancer: Int. J. Cancer.

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Abstract

A network of autocrine and paracrine signals defines B cell homeostasis and is thought to be involved in transformation processes. Investigating interactions of these microenvironmental factors and their relation to proto-oncogenes as c-Myc (MYC) is fundamental to understand the biology of B cell lymphoma. Therefore, B cells with conditional MYC expression were stimulated with CD40L, insulin-like ...

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Item type:Article
Date:1 March 2017
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Statistische Bioinformatik (Prof. Spang)
Identification Number:
ValueType
27668411PubMed ID
10.1002/ijc.30444DOI
Keywords:NF-KAPPA-B; C-MYC; GENE-EXPRESSION; STAT3; ACTIVATION; SURVIVAL; LYMPHOCYTES; GROWTH; CYCLE; IDENTIFICATION; toll-like receptor; interleukin; cyclin-dependent kinase; B cell proliferation
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:34825
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