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Comprehensive analysis of transitions in ribosomal DNA chromatin states in S. cerevisiae during different growth phases

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Babl, Virginia-Lorena
Date of publication of this fulltext: 11 Jan 2017 07:58

Abstract (English)

In the nucleus of eukaryotes DNA is assembled into a large nucleoprotein complex, called chromatin. Histones form the basic chromatin component, the nucleosome. Nucleosomes impair the access of proteins to DNA and may interfere with DNA-dependent processes such as transcription, replication and DNA repair. To make DNA accessible, chromatin has to be a highly dynamic structure. How genomic loci ...


Translation of the abstract (German)

Im Zellkern von Eukaryoten liegt die DNA in einem Nukleoproteinkomplex, dem Chromatin vor. Die Hauptkomponenten des Chromatins sind Nukleosomen, die aus Histonproteinen und DNA gebildet werden. Die Assemblierung der DNA in Nukleosomen behindert den Zugang von Proteinen zur DNA und konkurriert mit DNA-abhängigen Prozessen wie Transkription, Replikation und DNA Reparatur. Um diese essentiellen ...


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