Go to content
UR Home

Early dissemination seeds metastasis in breast cancer

Hosseini, H., Obradovic, M. M., Hoffmann, M., Harper, K. L., Sosa, M. S., Werner-Klein, M., Nanduri, L. K., Werno, C., Ehrl, C., Maneck, M., Patwary, N., Haunschild, G., Guzvic, M., Reimelt, C., Grauvogl, Michael, Eichner, N., Weber, F., Hartkopf, A. D., Taran, F. A., Brucker, S. Y., Fehm, T., Rack, B., Buchholz, S., Spang, Rainer, Meister, Gunter, Aguirre-Ghiso, J. A. and Klein, Christoph A. (2016) Early dissemination seeds metastasis in breast cancer. Nature 540, pp. 552-558.

Full text not available from this repository.

at PubMed

at publisher (via DOI)

Other URL: http://www.nature.com/nature/journal/v540/n7634/full/nature20785.html


Accumulating data suggest that metastatic dissemination often occurs early during tumour formation, but the mechanisms of early metastatic spread have not yet been addressed. Here, by studying metastasis in a HER2-driven mouse breast cancer model, we show that progesterone-induced signalling triggers migration of cancer cells from early lesions shortly after HER2 activation, but promotes ...


Export bibliographical data

Item type:Article
Date:22 December 2016
Institutions:Medicine > Lehrstuhl für experimentelle Medizin und Therapieverfahren
Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Statistische Bioinformatik (Prof. Spang)
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I > Prof. Dr. Gunter Meister
Identification Number:
27974799PubMed ID
Keywords:metastasis, breast cancer
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:35249
Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons