Dukorn, Stefanie, Littmann, Timo, Keller, Max, Kuhn, Kilian K., Cabrele, Chiara 
, Baumeister, Paul, Bernhardt, Günther and Buschauer, Armin
(2017)
Fluorescence- and radio-labeling of Lys4,Nle17,30hPP yields molecular tools for the NPY Y4 receptor.
Bioconjugate Chemistry.
Full text not available from this repository.
Other URL: https://www.ncbi.nlm.nih.gov/pubmed/28345900
Abstract
The neuropeptide Y (NPY) Y-4 receptor (Y4R) is involved in energy homeostasis and considered a potential drug target for the treatment of obesity. Only a few molecular tools, i.e., radiolabeled and fluorescent ligands, for the investigation of the Y4R were reported. Previously, [Lys(4)]hPP proved to be an appropriate full-length PP analog to prepare a fluorescent ligand by derivatization at the ...
Export bibliographical data
| Item type: | Article | ||||||
|---|---|---|---|---|---|---|---|
| Date: | 27 March 2017 | ||||||
| Additional Information (public): | Supplementary material available online | ||||||
| Institutions: | Chemistry and Pharmacy > Institute of Pharmacy Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) | ||||||
| Projects: | GRK 1910, Graduiertenkolleg "Medicinal Chemistry of Selective GPCR Ligands" | ||||||
| Identification Number: |
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| Keywords: | PANCREATIC-POLYPEPTIDE RECEPTORS; HIGH-AFFINITY RADIOLIGAND; NEUROPEPTIDE-Y; FUNCTIONAL EXPRESSION; AGONIST BINDING; HIGHLY POTENT; LIGANDS; ANALOGS; RAT; ANTAGONISTS; | ||||||
| Dewey Decimal Classification: | 500 Science > 540 Chemistry & allied sciences | ||||||
| Status: | Published | ||||||
| Refereed: | Yes, this version has been refereed | ||||||
| Created at the University of Regensburg: | Yes | ||||||
| Item ID: | 35478 |
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