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Assessing in silico the recruitment and functional spectrum of bacterial enzymes from secondary metabolism

Merkl, Rainer, Verprinsky, Valery, Plach, Maximilian G. and Heizinger, Leonhard (2017) Assessing in silico the recruitment and functional spectrum of bacterial enzymes from secondary metabolism. BMC Evolutionary Biology 17 (36), pp. 1-15.

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Date of publication of this fulltext: 21 Apr 2017 13:32

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Other URL: https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-017-0886-2

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

Background: Microbes, plants, and fungi synthesize an enormous number of metabolites exhibiting rich chemical diversity. For a high-level classification, metabolism is subdivided into primary (PM) and secondary (SM) metabolism. SM products are often not essential for survival of the organism and it is generally assumed that SM enzymes stem from PM homologs. Results: We wanted to assess ...

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Item type:Article
Date:26 January 2017
Institutions:Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Rainer Merkl
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1186/s12862-017-0886-2DOI
Keywords:CHORISMATE-UTILIZING ENZYMES; EVOLUTION; CLASSIFICATION; BIOSYNTHESIS; INFORMATION; DIVERSITY; PATHWAYS; OPERONS; GENOMES; Primary metabolism; Secondary metabolism; Enzyme evolution; Enzyme design
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35573
Owner only: item control page

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