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Assessing in silico the recruitment and functional spectrum of bacterial enzymes from secondary metabolism

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Merkl, Rainer ; Verprinsky, Valery ; Plach, Maximilian G. ; Heizinger, Leonhard
Date of publication of this fulltext: 21 Apr 2017 13:32


Background: Microbes, plants, and fungi synthesize an enormous number of metabolites exhibiting rich chemical diversity. For a high-level classification, metabolism is subdivided into primary (PM) and secondary (SM) metabolism. SM products are often not essential for survival of the organism and it is generally assumed that SM enzymes stem from PM homologs. Results: We wanted to assess ...


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