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Multistimulation Group Therapy in Alzheimer’s Disease Promotes Changes in Brain Functioning
Baglio, Francesca
, Griffanti, Ludovica
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(2015)
Multistimulation Group Therapy in Alzheimer’s Disease Promotes Changes in Brain Functioning.
Neurorehabilitation and Neural Repair 29, S. 13-24.
Veröffentlichungsdatum dieses Volltextes: 11 Mai 2017 12:48
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.35651
Zusammenfassung
Background. The growing social emergency represented by Alzheimer's disease (AD) and the lack of medical treatments able to modify the disease course have kindled the interest in nonpharmacological therapies. Objective. We introduced a novel nonpharmacological approach for people with AD (PWA) named Multidimensional Stimulation group Therapy (MST) to improve PWA condition in different disease ...
Background. The growing social emergency represented by Alzheimer's disease (AD) and the lack of medical treatments able to modify the disease course have kindled the interest in nonpharmacological therapies. Objective. We introduced a novel nonpharmacological approach for people with AD (PWA) named Multidimensional Stimulation group Therapy (MST) to improve PWA condition in different disease domains: cognition, behavior, and motor functioning. Methods. Enrolling 60 PWA in a mild to moderate stage of the disease, we evaluated the efficacy of MST with a randomized-controlled study. Neuropsychological and neurobehavioral measures and functional magnetic resonance imaging (fMRI) data were considered as outcome measures. Results. The following significant intervention-related changes were observed: reduction in Neuropsychiatric Inventory scale score, improvement in language and memory subscales of Alzheimer's Disease Assessment Scale-Cognitive subscale, and increased fMRI activations in temporal brain areas, right insular cortex, and thalamus. Conclusions. Cognitive-behavioral and fMRI results support the notion that MST has significant effects in improving PWA cognitive-behavioral status by restoring neural functioning.
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Details
| Dokumentenart | Artikel | ||||
| Titel eines Journals oder einer Zeitschrift | Neurorehabilitation and Neural Repair | ||||
| Verlag: | SAGE PUBLICATIONS INC | ||||
|---|---|---|---|---|---|
| Ort der Veröffentlichung: | THOUSAND OAKS | ||||
| Band: | 29 | ||||
| Seitenbereich: | S. 13-24 | ||||
| Datum | 2015 | ||||
| Institutionen | Medizin > Institut für Epidemiologie und Präventivmedizin | ||||
| Identifikationsnummer |
| ||||
| Stichwörter / Keywords | RANDOMIZED CONTROLLED-TRIAL; MILD COGNITIVE IMPAIRMENT; PSYCHOLOGICAL SYMPTOMS; DEMENTIA; STIMULATION; EXERCISE; EFFICACY; PEOPLE; CST; INTERVENTIONS; Alzheimer's disease; rehabilitation; occupational therapy; recreation therapy; cognitive therapy; magnetic resonance imaging; MRI; functional MRI; language | ||||
| Dewey-Dezimal-Klassifikation | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin | ||||
| Status | Veröffentlicht | ||||
| Begutachtet | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden | Ja | ||||
| URN der UB Regensburg | urn:nbn:de:bvb:355-epub-356510 | ||||
| Dokumenten-ID | 35651 |
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