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Dynamic interactions between PAR-aPKC complex and Crb complex in Drosophila epithelial cells

Sun, Rui (2018) Dynamic interactions between PAR-aPKC complex and Crb complex in Drosophila epithelial cells. PhD, Universität Regensburg.

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Date of publication of this fulltext: 16 Oct 2018 07:00

Abstract (English)

Epithelial cell polarity is one of the key prerequisites for the establishment of multicellular organisms. The apical-basal polarity of epithelia is controlled by evolutionarily conserved complexes which determine an apical versus a basolateral domain. The PAR-aPKC complex (Baz/PAR-3-PAR-6-aPKC) defines together with the Crumbs complex (Crb-Sdt/Pals1-PATJ) the apical plasma membrane domain of the ...

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Translation of the abstract (German)

Die Polarität der Epithelzellen ist eine der wichtigsten Voraussetzungen für die Enwicklung multizellulärer Organismen. Die apikal-basale Polarität des Epithels wird von evolutionär konservierten Komplexen kontrolliert, die eine apikale und eine basolaterale Domäne bestimmen. Der PAR-aPKC-Komplex (Baz / PAR-3-PAR-6-aPKC) definiert gemeinsam mit dem Crb-Sdt / Pals1-PATJ Komplex die apikale ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:16 October 2018
Referee:Prof. Dr. Dr. Michael P. Krahn
Date of exam:10 October 2017
Institutions:Biology, Preclinical Medicine > Institut für Anatomie > Lehrstuhl für Molekulare und zelluläre Anatomie
Keywords:Drosophila, epithelial polarity, Crb complex, Baz/PAR-aPKC complex, dynamics
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36232
Owner only: item control page

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