AGeNNT: annotation of enzyme families by means of refined neighborhood networks

URN to cite this document:: urn:nbn:de:bvb:355-epub-366573
DOI to cite this document:: 10.5283/epub.36657

Kandlinger, Florian ; Plach, Maximilian G. ; Merkl, Rainer

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Date of publication of this fulltext: 30 Jan 2018 09:01

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Abstract

Background: Large enzyme families may contain functionally diverse members that give rise to clusters in a sequence similarity network (SSN). In prokaryotes, the genome neighborhood of a gene-product is indicative of its function and thus, a genome neighborhood network (GNN) deduced for an SSN provides strong clues to the specific function of enzymes constituting the different clusters. The ...