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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-498968
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.36969
Alternative Links zum Volltext:DOI
Zusammenfassung
The mean (SD) unbound fraction of moxifloxacin in plasma from patients with severe sepsis or septic shock was determined by ultrafiltration to 85.5±3.0% (range 81.9 and 91.6%) indicating a decreased protein binding of moxifloxacin in this population compared with the value of 58–60% provided in the Summary of Product Characteristics. However, previous investigations neglected the influence of pH ...
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