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Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity

DeFilipp, Z., Peled, J. U., Li, S., Mahabamunuge, J., Dagher, Z., Slingerland, A. E., Del Rio, C., Valles, B., Kempner, M. E., Smith, M., Brown, J., Dey, B. R., El-Jawahri, A., McAfee, S. L., Spitzer, T. R., Ballen, K. K., Sung, A. D., Dalton, T. E., Messina, J. A., Dettmer, Katja, Liebisch, G., Oefner, Peter J., Taur, Y., Pamer, E. G., Holler, E., Mansour, M. K., van den Brink, M. R. M., Hohmann, E., Jenq, R. R. and Chen, Y. B. (2018) Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity. Blood Advances 2 (7), pp. 745-753.

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Date of publication of this fulltext: 06 Apr 2018 06:47

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Other URL: http://www.bloodadvances.org/content/2/7/745.long?sso-checked=true


Abstract

We hypothesized that third-party fecal microbiota transplantation (FMT) may restore intestinal microbiome diversity after allogeneic hematopoietic cell transplantation (allo-HCT). In this open-label single-group pilot study, 18 subjects were enrolled before allo-HCT and planned to receive third-party FMT capsules. FMT capsules were administered no later than 4 weeks after neutrophil engraftment, ...

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Item type:Article
Date:10 April 2018
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Identification Number:
ValueType
29592876PubMed ID
10.1182/bloodadvances.2018017731DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:37002
Owner only: item control page

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