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Investigating the modulation of genetic effects on late AMD by age and sex: Lessons learned and two additional loci

Winkler, Thomas W., Brandl, Caroline, Grassmann, Felix, Gorski, Mathias, Stark, Klaus, Loss, Julika, Weber, Bernhard H. F. and Heid, Iris M. (2018) Investigating the modulation of genetic effects on late AMD by age and sex: Lessons learned and two additional loci. PLoS ONE 13 (3), e0194321.

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Date of publication of this fulltext: 15 May 2018 10:41

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Other URL: http://doi.org/10.1371/journal.pone.0194321, http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194321


Abstract

Late-stage age-related macular degeneration (AMD) is the leading cause of visual impairment in the elderly with a complex etiology. The most important non-modifiable risk factors for onset and progression of late AMD are age and genetic risk factors, however, little is known about the interplay between genetics and age or sex. Here, we conducted a large-scale age- and sex-stratified genome-wide ...

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Item type:Article
Date:12 March 2018
Institutions:Medicine > Institut für Epidemiologie und Präventivmedizin > Lehrstuhl für Genetische Epidemiologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0194321DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37327
Owner only: item control page

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