Abstiens, Kathrin 
, Gregoritza, Manuel and Goepferich, Achim
(2018)
Ligand Density and Linker Length are Critical Factors for Multivalent Nanoparticle−Receptor Interactions.
ACS Applied Materials & Interfaces 11 (1), pp. 1311-1320.
Full text not available from this repository.
Abstract
Although there are a large number of studies available for the evaluation of the therapeutic efficacy of targeted polymeric nanoparticles, little is known about the critical attributes that can further influence their uptake into target cells. In this study, varying cRGD ligand densities (0–100% surface functionalization) were combined with different poly(ethylene glycol) (PEG) spacer lengths ...
Export bibliographical data
| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 6 December 2018 | ||||
| Institutions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich) | ||||
| Identification Number: |
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| Keywords: | integrin targeting; linker length; multivalency; polymeric nanoparticles; uptake efficiency | ||||
| Dewey Decimal Classification: | 600 Technology > 615 Pharmacy | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 38261 |
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