Moschall, Rebecca, Rass, Mathias, Rossbach, Oliver, Lehmann, Gerhard, Kullmann, Lars, Eichner, Norbert, Strauss, Daniela, Meister, Gunter, Schneuwly, Stephan, Krahn, Michael P and Medenbach, Jan (2018) Drosophila Sister-of-Sex-lethal reinforces a male-specific gene expression pattern by controlling Sex-lethal alternative splicing. Nucleic Acids Research 2018 (1), pp. 1-13.
| License: Creative Commons Attribution Non-commercial 4.0 Download (4MB) |
Other URL: http://doi.org/10.1093/nar/gky1284, https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gky1284/5264285
Abstract
In Drosophila, female development is governed by a single RNA-binding protein, Sex-lethal (Sxl), that controls the expression of key factors involved in dosage compensation, germline homeostasis and the establishment of female morphology and behaviour. Sxl expression in female flies is maintained by an auto-regulatory, positive feedback loop with Sxl controlling splicing of its own mRNA. Until ...
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| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 27 December 2018 | ||||
| Institutions: | Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I | ||||
| Projects: | Open Access Publizieren (DFG) | ||||
| Identification Number: |
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| Keywords: | Gene Regulation, Chromatin and Epigenetics | ||||
| Dewey Decimal Classification: | 500 Science > 570 Life sciences | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 38274 |
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