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fMRI with Central Vision Loss: Effects of Fixation Locus and Stimulus Type

Plank, Tina ; Frolo, Jozef ; Brandl-Rühle, Sabine ; Renner, Agnes B. ; Jägle, Herbert ; Greenlee, Mark W.


Purpose In patients with central visual field scotomata, a large part of visual cortex is not adequately stimulated. Patients often use a new eccentric fixation area on intact peripheral retina (preferred retinal locusPRL) that functions as a pseudo-fovea. We used functional magnetic resonance imaging (fMRI) to examine whether stimulating this pseudo-fovea leads to increased activation or altered ...


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