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Independent impedimetric analysis of two cell populations co-cultured on opposite sides of a porous support

Hajek, Kathrin ; Wegener, Joachim



Abstract

The transepithelial or -endothelial electrical resistance (TEER) is a very common and routinely recorded parameter describing the expression of barrier-forming cell-cell contacts (tight junctions) in quantitative terms. To determine TEER, barrier-forming cell monolayers are cultured on porous filter supports that separate two fluid compartments. The frequency-dependent impedance of the cell layer ...

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