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Macrophage-Derived Chemokine: A Putative Marker of Pharmacological Therapy Response in Major Depression?

Milenkovic, Vladimir M., Sarubin, Nina, Hilbert, Sven, Baghai, Thomas C., Stöffler, Friederike, Lima-Ojeda, Juan M., Manook, André, Almeqbaali, Khalifa, Wetzel, Christian H., Rupprecht, Rainer and Nothdurfter, Caroline (2017) Macrophage-Derived Chemokine: A Putative Marker of Pharmacological Therapy Response in Major Depression? Neuroimmunomodulation 24 (2), pp. 106-112.

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Other URL: http://doi.org/10.1159/000479739


Abstract

Introduction: Inflammatory processes play an important and complex role in the pathophysiology of major depressive disorder (MDD), but, so far, no specific investigation of chemokines exists. Methods: In this study, we investigated the changes of plasma chemokine levels (eotaxin-1, eotaxin-3, IP-10, MCP-1, MCP-4, MDC, MIP-1 alpha, MIP-1 beta, and TARC) in 47 MDD patients before (PRE) and after 1 ...

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Item type:Article
Date:2017
Institutions:Psychology and Pedagogy > Institut für Psychologie
Identification Number:
ValueType
10.1159/000479739DOI
Keywords:BIPOLAR DISORDER; METAANALYSIS; SCHIZOPHRENIA; INFLAMMATION; CYTOKINES; ANTIDEPRESSANTS; BIOMARKER; KNOCKOUT; EFFICACY; DISEASE; Chemokines; Macrophage-derived chemokine; Major depression; Antidepressant; Therapy response
Dewey Decimal Classification:100 Philosophy & psychology > 150 Psychology
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38844
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