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Influenza A virus mimetic nanoparticles trigger selective cell uptake

Maslanka-Figueroa, Sara ; Veser, Anika ; Abstiens, Kathrin ; Fleischmann, Daniel ; Göpferich, Achim



Abstract

Poor target cell specificity is currently a major shortcoming of nanoparticles (NPs) used for biomedical applications. It causes significant material loss to off-target sites and poor availability at the intended delivery site. To overcome this limitation, we designed particles that identify cells in a virus-like manner. As a blueprint, we chose a mechanism typical of influenza A virus particles ...

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