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Expression and Functional Significance of the Ca2+-Activated Cl- Channel ANO6 in Dendritic Cells

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Szteyn, K. ; Schmid, Evi ; Nurbaeva, M.K. ; Wang, Wenting ; Münzer, P. ; Kunzelmann, Karl ; Lang, Florian ; Shumilina, E.
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Date of publication of this fulltext: 23 Oct 2019 09:07


Background/Aims: Migration of dendritic cells (DCs), antigen presenting cells that link innate and adaptive immunity, is critical for initiation of immune responses. DC migration is controlled by the activity of different ion channels, which mediate Ca2+ flux or set the membrane potential. Moreover, cell migration requires local volume changes at the leading and rear end of travelling cells, ...


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