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Reduction of Tinnitus Severity by the Centrally Acting Muscle Relaxant Cyclobenzaprine: An Open-Label Pilot Study

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Coelho, Claudia ; Figueiredo, Ricardo ; Frank, Elmar ; Burger, Julia ; Schecklmann, Martin ; Landgrebe, Michael ; Langguth, Berthold ; Belen Elgoyhen, Ana
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Date of publication of this fulltext: 23 Oct 2019 10:20


Tinnitus, the phantom perception of sounds, is a highly prevalent disorder. Although a wide variety of drugs have been investigated off label for the treatment of tinnitus, there is no approved pharmacotherapy. We report an open-label exploratory pilot study to assess the effect of muscle relaxants acting on the central nervous system on tinnitus patients. Cyclobenzaprine at high (30 mg) and low ...


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