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Differential Impact of ApoE ε4 on Cortical Activation During Famous Face Recognition in Cognitively Intact Individuals and Patients With Amnestic Mild Cognitive Impairment

Frank, Gabriele ; Hennig-Fast, Kristina ; Klünemann, Hans H. ; Schmitz, Gerd ; Greenlee, Mark W.



Abstract

This study explores the neurofunctional correlates of the recognition of famous faces in patients with amnestic mild cognitive impairment (aMCI) and healthy controls depending on the genetic risk factor, Apolipoprotein E (ApoE) epsilon 4. An event-related functional magnetic resonance imaging experiment was conducted while participants discriminated between famous and nonfamous faces. We compared ...

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