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Differential Impact of ApoE ε4 on Cortical Activation During Famous Face Recognition in Cognitively Intact Individuals and Patients With Amnestic Mild Cognitive Impairment

Frank, Gabriele ; Hennig-Fast, Kristina ; Klünemann, Hans H. ; Schmitz, Gerd ; Greenlee, Mark W.


This study explores the neurofunctional correlates of the recognition of famous faces in patients with amnestic mild cognitive impairment (aMCI) and healthy controls depending on the genetic risk factor, Apolipoprotein E (ApoE) e4. An eventrelated functional magnetic resonance imaging experiment was conducted while participants discriminated between famous and nonfamous faces. We compared the ...


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