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Pol5 is required for recycling of small subunit biogenesis factors and for formation of the peptide exit tunnel of the large ribosomal subunit

URN to cite this document:
urn:nbn:de:bvb:355-epub-415269
Braun, Christina M ; Hackert, Philipp ; Schmid, Catharina E ; Bohnsack, Markus T ; Bohnsack, Katherine E ; Perez-Fernandez, Jorge
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Date of publication of this fulltext: 07 Feb 2020 12:03


Abstract

More than 200 assembly factors (AFs) are required for the production of ribosomes in yeast. The stepwise association and dissociation of these AFs with the pre-ribosomal subunits occurs in a hierarchical manner to ensure correct maturation of the pre-rRNAs and assembly of the ribosomal proteins. Although decades of research have provided a wealth of insights into the functions of many AFs, others ...

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