Pol5 is required for recycling of small subunit biogenesis factors and for formation of the peptide exit tunnel of the large ribosomal subunit

URN to cite this document:: urn:nbn:de:bvb:355-epub-415269
DOI to cite this document:: 10.5283/epub.41526

Braun, Christina M. ; Hackert, Philipp ; Schmid, Catharina E. ; Bohnsack, Markus T.

; Bohnsack, Katherine E.

; Perez-Fernandez, Jorge

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Date of publication of this fulltext: 07 Feb 2020 12:03

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Abstract

More than 200 assembly factors (AFs) are required for the production of ribosomes in yeast. The step-wise association and dissociation of these AFs with the pre-ribosomal subunits occurs in a hierarchical manner to ensure correct maturation of the prerRNAs and assembly of the ribosomal proteins. Although decades of research have provided a wealth of insights into the functions of many AFs, others ...