Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode
Sawatzky, Edgar, Wehle, Sarah, Kling, Beata, Wendrich, Jan, Bringmann, Gerhard, Sotriffer, Christoph A., Heilmann, Jörg and Decker, Michael (2016) Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode. Journal of Medicinal Chemistry 59 (5), pp. 2067-2082.Date of publication of this fulltext: 17 Mar 2020 11:28
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| Item type | Article | ||||
| Journal or Publication Title | Journal of Medicinal Chemistry | ||||
| Publisher: | AMER CHEMICAL SOC | ||||
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| Place of Publication: | WASHINGTON | ||||
| Volume: | 59 | ||||
| Number of Issue or Book Chapter: | 5 | ||||
| Page Range: | pp. 2067-2082 | ||||
| Date | 2016 | ||||
| Institutions | Chemistry and Pharmacy > Institute of Pharmacy Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann) | ||||
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| Keywords | AMYLOID-BETA-PEPTIDE; NITROGEN-BRIDGEHEAD COMPOUNDS; ALZHEIMERS-DISEASE; OXIDATIVE STRESS; CHOLINESTERASE-INHIBITORS; CHOLESTEROL ESTERASE; HUMAN ACETYLCHOLINESTERASE; MOLECULAR RECOGNITION; BIOLOGICAL EVALUATION; GENETIC ALGORITHM; | ||||
| Dewey Decimal Classification | 600 Technology > 615 Pharmacy | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 42394 |
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