Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode
Article
Sawatzky, Edgar, Wehle, Sarah, Kling, Beata, Wendrich, Jan, Bringmann, Gerhard, Sotriffer, Christoph A., Heilmann, Jörg and Decker, Michael (2016) Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode. Journal of Medicinal Chemistry 59 (5), pp. 2067-2082.Alternative links to fulltext
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| Item type | Article | ||||
| Journal or Publication Title | Journal of Medicinal Chemistry | ||||
| Publisher | AMER CHEMICAL SOC | ||||
| Place of Publication | WASHINGTON | ||||
| Volume | 59 | ||||
| Number of Issue or Book Chapter | 5 | ||||
| Page Range | pp. 2067-2082 | ||||
| Date | 2016 | ||||
| Date of publication | 17 Mar 2020 11:28 | ||||
| Institutions | Chemistry and Pharmacy > Institute of Pharmacy Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann) | ||||
| Identification Number |
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| Keywords | AMYLOID-BETA-PEPTIDE; NITROGEN-BRIDGEHEAD COMPOUNDS; ALZHEIMERS-DISEASE; OXIDATIVE STRESS; CHOLINESTERASE-INHIBITORS; CHOLESTEROL ESTERASE; HUMAN ACETYLCHOLINESTERASE; MOLECULAR RECOGNITION; BIOLOGICAL EVALUATION; GENETIC ALGORITHM; | ||||
| Dewey Decimal Classification | 600 Technology > 615 Pharmacy | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 42394 |
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