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Nanoparticles Mimicking Viral Cell Recognition Strategies Are Superior Transporters into Mesangial Cells

Maslanka Figueroa, Sara ; Fleischmann, Daniel ; Beck, Sebastian ; Tauber, Philipp ; Witzgall, Ralph ; Schweda, Frank ; Goepferich, Achim
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Date of publication of this fulltext: 18 Jun 2020 13:51


Abstract

Poor drug availability in the tissue of interest is a frequent cause of therapy failure. While nanotechnology has developed a plethora of nanocarriers for drug transport, their ability to unequivocally identify cells of interest remains moderate. Viruses are the ideal nanosized carriers as they are able to address their embedded nucleic acids with high specificity to their host cells. Here, it is ...

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