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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-442371
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.44237
Zusammenfassung
Background: The epidermal growth factor receptor (EGFR) signaling pathway is genetically activated in approximately 50% of glioblastomas (GBs). Its inhibition has been explored clinically but produced disappointing results, potentially due to metabolic effects that protect GB cells against nutrient deprivation and hypoxia. Here, we hypothesized that EGFR activation could disable metabolic ...
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