1,25-dihydroxyvitamin-D3 but not the clinically applied marker 25-hydroxyvitamin-D3 predicts survival after stem cell transplantation

URN to cite this document:: urn:nbn:de:bvb:355-epub-447344
DOI to cite this document:: 10.5283/epub.44734

Peter, Katrin

; Siska, Peter J. ; Roider, Tobias ; Matos, Carina ; Bruns, Heiko ; Renner, Kathrin ; Singer, Katrin ; Weber, Daniela ; Güllstorf, Martina ; Kröger, Nicolaus ; Wolff, Daniel

; Herr, Wolfgang ; Ayuk, Francis ; Holler, Ernst ; Stark, Klaus ; Heid, Iris M. ; Kreutz, Marina

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Date of publication of this fulltext: 05 Feb 2021 06:47

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Abstract

The serum level of 25-hydroxyvitamin-D3 is accepted as marker for a person's vitamin D status but its role for the outcome of allogeneic hematopoietic stem cell transplantation (HSCT) is controversially discussed. The impact of 1,25-dihydroxyvitamin-D3 on HSCT outcome, however, has never been studied. In a discovery cohort of 143 HSCT patients we repeatedly (day -16 to 100) measured ...