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1,25-dihydroxyvitamin-D3 but not the clinically applied marker 25-hydroxyvitamin-D3 predicts survival after stem cell transplantation

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Peter, Katrin ; Siska, Peter J. ; Roider, Tobias ; Matos, Carina ; Bruns, Heiko ; Renner, Kathrin ; Singer, Katrin ; Weber, Daniela ; Güllstorf, Martina ; Kröger, Nicolaus ; Wolff, Daniel ; Herr, Wolfgang ; Ayuk, Francis ; Holler, Ernst ; Stark, Klaus ; Heid, Iris M. ; Kreutz, Marina
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 05 Feb 2021 06:47

This publication is part of the DEAL contract with Springer.


The serum level of 25-hydroxyvitamin-D3 is accepted as marker for a person's vitamin D status but its role for the outcome of allogeneic hematopoietic stem cell transplantation (HSCT) is controversially discussed. The impact of 1,25-dihydroxyvitamin-D3 on HSCT outcome, however, has never been studied. In a discovery cohort of 143 HSCT patients we repeatedly (day -16 to 100) measured ...


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