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A Predictive Model for Progression of CKD to Kidney Failure Based on Routine Laboratory Tests

Zacharias, Helena U. ; Altenbuchinger, Michael ; Schultheiss, Ulla T. ; Raffler, Johannes ; Kotsis, Fruzsina ; Ghasemi, Sahar ; Ali, Ibrahim ; Kollerits, Barbara ; Metzger, Marie ; Steinbrenner, Inga ; Sekula, Peggy ; Massy, Ziad A. ; Combe, Christian ; Kalra, Philip A. ; Kronenberg, Florian ; Stengel, Bénédicte ; Eckardt, Kai-Uwe ; Köttgen, Anna ; Schmid, Matthias ; Gronwald, Wolfram ; Oefner, Peter J.



Abstract

Rationale & Objective: Stratification of chronic kidney disease (CKD) patients at risk for progressing to kidney failure requiring kidney replacement therapy (KFRT) is important for clinical decision-making and trial enrollment. Study Design: Four independent prospective observational cohort studies. Setting & Participants: The development cohort comprised 4,915 CKD patients, and 3 independent ...

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