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Drugs linked to plasma homoarginine in chronic kidney disease patients—a cross-sectional analysis of the German Chronic Kidney Disease cohort

Maas, Renke ; Mieth, Maren ; Titze, Stephanie I. ; Hübner, Silvia ; Fromm, Martin F. ; Kielstein, Jan T. ; Schmid, Matthias ; Köttgen, Anna ; Kronenberg, Florian ; Krane, Vera ; Hausknecht, Birgit ; Eckardt, Kai-Uwe ; Schneider, Markus P. ; Oefner, Peter J. ; Gronwald, Wolfram



Zusammenfassung

Background Elevated plasma concentrations of symmetric and asymmetric dimethylarginine (SDMA and ADMA, respectively) and a lower plasma concentration of the structurally related homoarginine are commonly observed in patients with chronic kidney disease (CKD) and independently predict total mortality as well as progression of renal disease. We aimed to identify drugs that may alter this adverse ...

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