Helferich, Anika M. ; Brockmann, Sarah J. ; Reinders, Jörg ; Deshpande, Dhruva ; Holzmann, Karlheinz ; Brenner, David ; Andersen, Peter M. ; Petri, Susanne ; Thal, Dietmar R. 
; Michaelis, Jens ; Otto, Markus ; Just, Steffen ; Ludolph, Albert C. ; Danzer, Karin M. ; Freischmidt, Axel ; Weishaupt, Jochen H.
; Michaelis, Jens ; Otto, Markus ; Just, Steffen ; Ludolph, Albert C. ; Danzer, Karin M. ; Freischmidt, Axel ; Weishaupt, Jochen H. 
Zusammenfassung
Genetic and functional studies suggest diverse pathways being affected in the neurodegenerative disease amyotrophic lateral sclerosis (ALS), while knowledge about converging disease mechanisms is rare. We detected a downregulation of microRNA-1825 in CNS and extra-CNS system organs of both sporadic (sALS) and familial ALS (fALS) patients. Combined transcriptomic and proteomic analysis revealed ...
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