Go to content
UR Home

Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS

Helferich, Anika M. ; Brockmann, Sarah J. ; Reinders, Jörg ; Deshpande, Dhruva ; Holzmann, Karlheinz ; Brenner, David ; Andersen, Peter M. ; Petri, Susanne ; Thal, Dietmar R. ; Michaelis, Jens ; Otto, Markus ; Just, Steffen ; Ludolph, Albert C. ; Danzer, Karin M. ; Freischmidt, Axel ; Weishaupt, Jochen H.


Genetic and functional studies suggest diverse pathways being affected in the neurodegenerative disease amyotrophic lateral sclerosis (ALS), while knowledge about converging disease mechanisms is rare. We detected a downregulation of microRNA-1825 in CNS and extra-CNS system organs of both sporadic (sALS) and familial ALS (fALS) patients. Combined transcriptomic and proteomic analysis revealed ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons