Go to content
UR Home

Two isoforms of cyclic GMP-dependent kinase-I exhibit distinct expression patterns in the adult mouse dorsal root ganglion

Uchida, Hitoshi ; Matsumura, Shinji ; Katano, Tayo ; Watanabe, Masahiko ; Schlossmann, Jens ; Ito, Seiji



Abstract

cGMP-dependent kinase-I (cGKI) is known to regulate spinal pain processing. This enzyme consists of two isoforms (cGKI alpha and cGKI beta) that show distinct substrate specificity and tissue distribution. It has long been believed that the alpha isoform is exclusively expressed in the adult dorsal root ganglion. The aim of the present study was to reexamine the expression of cGKI isoforms in the ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons