Billot, Katy ; Coquil, Charlène ; Villiers, Benoit ; Josselin-Foll, Béatrice ; Desban, Nathalie ; Delehouzé, Claire ; Oumata, Nassima ; Le Meur, Yannick 
; Boletta, Alessandra ; Weimbs, Thomas ; Grosch, Melanie ; Witzgall, Ralph ; Saunier, Sophie ; Fischer, Evelyne ; Pontoglio, Marco ; Fautrel, Alain ; Mrug, Michal ; Wallace, Darren ; Tran, Pamela V. ; Trudel, Marie ; Bukanov, Nikolay ; Ibraghimov-Beskrovnaya, Oxana ; Meijer, Laurent
; Boletta, Alessandra ; Weimbs, Thomas ; Grosch, Melanie ; Witzgall, Ralph ; Saunier, Sophie ; Fischer, Evelyne ; Pontoglio, Marco ; Fautrel, Alain ; Mrug, Michal ; Wallace, Darren ; Tran, Pamela V. ; Trudel, Marie ; Bukanov, Nikolay ; Ibraghimov-Beskrovnaya, Oxana ; Meijer, Laurent 
Zusammenfassung
Following the discovery of (R)-roscovitine's beneficial effects in three polycystic kidney disease (PKD) mouse models, cyclin-dependent kinases (CDKs) inhibitors have been investigated as potential treatments. We have used various affinity chromatography approaches to identify the molecular targets of roscovitine and its more potent analog (S)-CR8 in human and murine polycystic kidneys. These ...
Nur für Besitzer und Autoren: Kontrollseite des Eintrags
Altmetric